Quinolones are synthetic broad-spectrum antibiotics which keep bacterial DNA from unwinding and duplicating. They are the most likely class of drugs to cause colonization of MRSA.
Recommended Resources
Quinolones and the Clinical Laboratory
The Centers for Disease Control and Prevention answers frequently asked questions including questions about fluoroquinolones and resistance.
http://www.cdc.gov/ncidod/dhqp/ar_lab_quinlolones.html
Quinolones for Unconcomplicated Avute Cystitis in Women
This review starts out with the postulation that there is no evidence in microbiological efficacy of quinolones for this type of cystitis in women, however, there is evidence of differences in range of adverse reactions.
http://www.cochrane.org/reviews/en/ab003597.html
Quinolones: A Comprehensive Review
Peer-reviewed article sets out to exhibit details about quinolones including its mechanism of action, pharmacokinetics, and a comparison of different generations.
http://www.aafp.org/afp/20020201/455.html
