The H2-receptor antagonists are often called H2 antagonist. They are a class of drugs which inhibit the action of histamine on the parietal cells , located in the stomach. This causes the production of acid in those cells to drop.
Recommended Resources
The Family Practice Notebook Presents details about H2 receptor antagonists which entail the brand names, mechanism, and efficacy, all in an easy-to-read outline format.
http://www.fpnotebook.com/GI/Pharm/H2RcptrAntgnst.htm
Contains data about both oral and intravenous H-2 antagonists, beginning with a list of brand names in the United States and in Canada. An explanation of how H2-receptor antagonists, or H2-blockers work and what the adverse effects may be.
http://www.mayoclinic.com/health/drug-information/DR601907
Histamine H2-receptor Antagonists
Outlines the uses, pharmacokinetics, therapeutic use, and effects of H2 antagonists, including a diagram of the pharmacological breakdown of the agent.
http://www.pharmacorama.com/en/Sections/Histamin_4.php
Provides details about ranitidine, which is known by the name Zantac, a histamine-2 blocker which is used to treat GERD and heartburn.
http://www.drugs.com/ranitidine.html
Tiotidine, H2 Receptor Inverse Agonist Binds to Inactive G-Protein
The full title of the article is Tiotidine, a Histamine H2 Receptor Inverse Agonist That Binds with High Affinity to an Inactive G-Protein–Coupled Form of the Receptor. Experimental Support for the Cubic Ternary Complex Model, and the full text of the article is made public for any to read here.
http://molpharm.aspetjournals.org/content/64/2/512.full.pdf
